Number in Human Cells Orc 1 Controls Centriole and Centrosome Copy
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چکیده
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منابع مشابه
Orc1 controls centriole and centrosome copy number in human cells.
Centrosomes, each containing a pair of centrioles, organize microtubules in animal cells, particularly during mitosis. DNA and centrosomes are normally duplicated once before cell division to maintain optimal genome integrity. We report a new role for the Orc1 protein, a subunit of the origin recognition complex (ORC) that is a key component of the DNA replication licensing machinery, in contro...
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